Do you support HTTP/3 and TLS 1.3?

Yes, we support both HTTP/3 and TLS 1.3 with our Windows 2022 Servers.
One of the new features Windows Server 2022 brings is native support for hosting HTTP/3 and TLS 1.3 services.
HTTP/3 is a major overhaul of HTTP with performance and security in mind. It uses QUIC as a transport (our HTTP server, http.sys, is using msquic) to gain the benefits of eliminated head of line blocking at the transport layer. This is a significant improvement over HTTP/2 which eliminated head of line blocking only at the HTTP layer with streams that allowed a single HTTP/2 connection to replace a set of HTTP/1.1 connections. HTTP/3 also benefits from many lessons learned in HTTP/2, such as simplifying the protocol by removing prioritization.